Anthropometric Measures Among Children and Teens With Classic 46,XX Congenital Adrenal Hyperplasia in Relation to Improvements in Diagnosis and Care
McCracken C, Kaabi O, Crawford M, Gardner MD, Getahun D, Goodman M, Sorouri Khorashad B, Lash TL, Roblin D, Vupputuri S, Yacoub R, Speiser PW, Lee PA, Sandberg DE
Congenital Adrenal Hyperplasia (CAH) is a condition a person is born with that affects how their body makes certain hormones. This study evaluated the growth trajectories of people with CAH compared to people without CAH. We looked at the electronic medical records of people with and without CAH in 3 different health systems, including Kaiser Permanente Georgia, and compared their height, weight, and body mass index over time. People with CAH had lower height percentiles at all time points, but there were improvements in outcomes for people born after physician treatment consensus guidelines were published in 2002. Although stunted growth may affect people with CAH, advances in diagnosis and care improved growth outcomes.